The prize was conferred during the 52nd Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT), which took place in Madrid, Spain.
The scientists discovered that the immune system could help repair intestinal damage caused by cancer treatments such as radiation, chemotherapy, and bone marrow transplantation. The study revealed that while the inflammatory molecule interferon-gamma (IFN-γ) has long been associated with gut injury, it can promote healing when paired with another immune molecule, interleukin-10 (IL-10).
“This award is very meaningful to us because it recognizes the importance of understanding how the immune system can actively support tissue repair during cancer therapy,” comments Julius Fischer, first author of the study.
“We hope that these insights will ultimately help develop strategies to protect patients from intestinal damage and make intensive treatments safer,” concludes Hendrik Poeck.
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To learn more about the EBMT- CTIWP Jon J. van Rood Award visit the site below:
https://www.ebmt.org/ebmt/news/apply-jon-j-van-rood-award
Within the Collaborative Research Centre/Transregio (CRC/TRR) 221 innovative immune modulation strategies will be investigated to separate GvHD from GvL effects in order to enhance the safety and efficacy of allo-HSCT in the future.