RETREAT PROGRAM

Thursday, May 2nd, 2024

Service projects       Chairs: t.b.a./t.b.a.

10.00 a.m.                Z01 – Büttner-Herold / Evert / Rosenwald

                                 Pathology workup of GvHD and GvL in mice and man

10.25 a.m.                Z02 –  Hoffmann / Winkler T. / Beilhack

                                 Animal engineering and complex transplantation models

10.50 a.m.                INF – Dandekar / Holler / Kehr / Kunz

                                 Data integration platform and systems medicine efforts to foster GvL & GvHD research

11.15 – 11.40 p.m.  Coffee break at „Gutshof Foyer“, ground floor (t.b.c.)

Projects – Section A Chairs:  t.b.a./t.b.a.

11.40 a.m.                 A01 – Reimann / Kremer

                                 Deciphering the role of HLA-DO in immune responses after allogeneic stem cell transplantation

12.05 p.m.                A02 – Thomas / Herr

                                 Efficacy and safety of HLA-DPB1-specific T-cell receptors as mediators of graft-versus-leukemia effect

12.30 a.m.                A03 – Hudecek / Einsele

                                 Advanced CAR T cell engineering to augment the graft-versus-leukemia effect of allogeneic HSCT

12.55 – 02.10 p.m.   Lunch break at „Gutshof Restaurant“, 1^st floor

Projects – Section A Chairs:  t.b.a./t.b.a.

02.10 p.m.                 A04 – Bumm / Mokhtari / Stuhler

                                  Novel tri-specific T-cell activating antibodies for personalized graft-versus-leukemia therapy

02.35 p.m.                 A06 –  Mougiakakos / Mackensen

                                  Metabolic stress related immune alterations with impact on graft- versus-leukemia effect in allogeneic stem-cell transplantation

03.00 p.m.                 A07 – Harrer / Gattinoni

                                  Enhancing graft-versus-leukemia responses by donor- derived CAR-modified CD8+ T memory stem cells

03.25 p.m.                 A08 – Poeck / Schmidl

                                  Timed targeting of cGAS / STING to improve tissue regeneration and anti-tumor responses following allo-HSCT

03.50 – 04.10 p.m.     Coffee break at „Gutshof Foyer“, ground floor (t.b.c.)

Projects – Section B Chairs:  t.b.a./t.b.a.

04.10 p.m.                  Associate Project –  Kilian Schober

                                   T cell receptors against immunodominant antigens in acute myeloid leukemia

04.35 p.m.                  B01 – Berberich-Siebelt / Spörl

                                   Therapeutic targeting of T-follicular cells in GvHD

05.15 – 06.30 p.m.      General assembly of PIs

07.30 p.m.                   Dinner for all participants at t.b.a.

Friday, May 3rd, 2024

  Projects – Section B Chairs:  t.b.a./t.b.a.

08.30 p.m.             B02 – Wajant

                             Targeting of TNFR2 and related molecules to separate GvHD from the GvL effect

08.55 a.m.             B03 – Hildner

                             Generation, molecular characteristics and effector mechanisms of CSF2+ T cells in graft-versus-host disease

09.20 a.m.             B04 – Distler / Jitschin

                             Aldehyde dehydrogenase 3A2 (ALDH3A2) as a novel regulator of inflammation and fibrotic tissue remodeling in sclerodermatous chronic graft-versus-host-                               disease

09.45 a.m.             B07 – Hoffmann / Rehli / Edinger

                              GvHD therapy with in vitro expanded donor regulatory T Cells

10.10 – 10.40 a.m.  Coffee break at „Gutshof Foyer“, ground floor (t.b.c.)

 Projects – Section B Chairs:  t.b.a./t.b.a.

10.40 a.m.              B08 – Feuerer

                               Harnessing tissue homeostasis-promoting functions of specialized regulatory T cells in graft-versus- host disease

11.05 a.m.              B09 – Gomez de Agüero / Beilhack

                              Regulation of tissue-resident myeloid cells controlling acute and chronic GvHD

11.30 a.m.              B10 – Winkler T. / Winkler J. / Wolff

                              Dysregulations of the B- lymphocyte compartment leading to chronic GvHD

11.55 – 01.10 p.m. Lunch break at „Gutshof Restaurant“, 1^st floor

 Projects – Section B Chairs:  t.b.a./t.b.a.

01.10 p.m.              B11 – Zernecke-Madsen / Beilhack

                              Targeting the reciprocal interaction of GvHD and atherosclerosis after allogeneic HSCT

01.35 p.m.              B12 – Kreutz / Bruns

                               Regulation of the immune balance during allogeneic hematopoietic stem cell transplantation (HSCT) by vitamin D3

02.00 p.m.              B13 – Weber / Gessner / Holler

                               Enterococci in allogeneic stem cell transplantation – indicators of loss of diversity or true GvHD pathogens?

02.25 p.m.              B14 –  Zaiß

                               Role of EGF-like growth factors in immune regulation and tissue homeostasis during Graft versus Host (GvH) Disease

About 02.50 p.m.   Farewell – Coffee at „Gutshof Foyer“, ground floor (t.b. c.)

To register, please contact:

Sabrina Bernhard-Linz

Universitätsklinikum Regensburg

Franz-Josef-Strauß-Allee 11

D – 93053 Regensburg

Phone: +49 (0) 941 944-5503

sabrina.bernhard-linz(at)ukr.de

 Retreat Venue:

Schloss Hohenkammer GmbH – „Gutshof-Saal“, 1st floor
Schlossstr. 20
85411 Hohenkammer
www.schlosshohenkammer.de
Phone: +49 (0)8137 934-0
Fax:     +49 (0)8137